On-admission SARS-CoV-2 RNAemia as a single potent predictive marker of critical condition development and mortality in COVID-19.

ABSTRACT:

Background

This study aimed to clarify how SARS-CoV-2 RNAemia is related to COVID-19 critical condition development and mortality in comparison with other predictive markers and scoring systems.

Methods

This is a retrospective cohort study conducted at Yokohama Municipal Citizen's Hospital and National Institute of Infectious Diseases. We recruited adult patients with COVID-19 admitted between March 2020 and January 2021. We compared RNAemia with clinical status on admission including scoring systems such as the 4C Mortality, CURB-65, and A-DROP, as well as the Ct value of the nasopharyngeal PCR, in predicting COVID-19 mortality and critical condition development.

Results

Of the 92 recruited patients (median age, 58; interquartile range, 45-71 years), 14 (14.9%) had R

SUBMITTER: Miki S 

PROVIDER: S-EPMC8277033 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature