Disseminated disease due to non-tuberculous mycobacteria in HIV positive patients: A retrospective case control study.

ABSTRACT:

Introduction

Disseminated infection due to non-tuberculous mycobacteria has been a major factor of mortality and comorbidity in HIV patients. Until 2018, U.S. American guidelines have recommended antimycobacterial prophylaxis in patients with low CD4 cell counts, a practice that has not been adopted in Europe. This study aimed at examining the impact of disseminated NTM disease on clinical outcome in German HIV patients with a severe immunodeficiency.

Materials and methods

In this retrospective case control study, HIV patients with disseminated NTM disease were identified by retrospective chart review and matched by their CD4 cell counts to HIV patients without NTM infection in a 1:1 alocation. Primary endpoints were mortality and time to first rehospitalisation. In addition

SUBMITTER: Wetzstein N 

PROVIDER: S-EPMC8277071 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature