Quantifying the Predictive Performance of Objectively Measured Physical Activity on Mortality in the UK Biobank.

ABSTRACT:

Background

Objective measures of physical activity (PA) derived from wrist-worn accelerometers are compared with traditional risk factors in terms of mortality prediction performance in the UK Biobank.

Method

A subset of participants in the UK Biobank study wore a tri-axial wrist-worn accelerometer in a free-living environment for up to 7 days. A total of 82 304 individuals over the age of 50 (439 707 person-years of follow-up, 1959 deaths) had both accelerometry data that met specified quality criteria and complete data on a set of traditional mortality risk factors. Predictive performance was assessed using cross-validated Concordance (C) for Cox regression models. Forward selection was used to obtain a set of best predictors of mortality.

Results

In univariate Cox

SUBMITTER: Leroux A 

PROVIDER: S-EPMC8277083 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature