MS/MS analysis of four scorpion venoms from Colombia: a descriptive approach.

ABSTRACT:

Background

Scorpions are widely known for the neurotoxic effects of their venoms, which contain peptides affecting ionic channels. Although Colombia is recognized for its scorpion diversity, only a few studies are available describing the venom content.

Methods

In this descriptive study, we analyzed the MS/MS sequence, electrophoretic and chromatographic profile linked to a bioinformatics analysis of the scorpions Chactas reticulatus (Chactidae), Opisthacanthus elatus (Hormuridae), Centruroides edwardsii (Buthidae) and Tityus asthenes (Buthidae) from Colombia.

Results

Each scorpion showed a specific electrophoretic and chromatographic profile. The electrophoretic profiles indicate the presence of high molecular mass compounds in all venoms,

SUBMITTER: Estrada-Gomez S 

PROVIDER: S-EPMC8277192 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature