A Comprehensive Pan-Cancer Analysis of RBM8A Based on Data Mining.

ABSTRACT:

Background

As a member of the exon junction complex (EJC), RNA-binding motif protein 8A (RBM8A) plays a crucial role in the maintenance of mRNA and multiple activities of an organism. Immunotherapy has been proven to be a staple type of cancer treatment. However, the role of RBM8A and immunity across cancer types is unclear.

Objective

This study aims to visualize the expression, prognosis, mutations, and coexpressed gene results of RBM8A across cancer types and to explore the link between RBM8A expression and immunity.

Methods

In this study, data were collected from multiple online databases. We analyzed the data using the HPA, UALCAN Database, COSMIC, cBioPortal, Cancer Regulome tools, Kaplan-Meier Plotter, and TIMER website.

Results

For the expression of RBM8

SUBMITTER: Mei N 

PROVIDER: S-EPMC8277506 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature