Association of Circulating Brain-Derived Neurotrophic Factor with Cognition among Adult Obese Population.

ABSTRACT:

Background

Obesity has a strong association with the risk of developing cognitive impairment and dementia at a later age. Brain-derived neurotrophic factor (BDNF) and its receptor appear to be important components in cognitive function and are also involved in energy homeostasis. The level of circulating BDNF and its association with cognition has yet to be delineated clearly. In this work we studied the association of circulating BDNF with cognition among the adult obese population.

Methods

The study involved 132 healthy participants between 18 and 40 years of age and of both sexes. The participants were categorized into an obesity group (n=66) and a non-obese group (n=66) based on their body mass index (Asian criteria). The level of cognitive performance was assessed by th

SUBMITTER: Katuri RB 

PROVIDER: S-EPMC8277590 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature