Low seroprevalence of COVID-19 in Lao PDR, late 2020.

ABSTRACT:

Background

In 2020 Lao PDR had low reported COVID-19 cases but it was unclear whether this masked silent transmission. A seroprevalence study was done August - September 2020 to determine SARS-CoV-2 exposure.

Methods

Participants were from the general community (n=2433) or healthcare workers (n=666) in five provinces and bat/wildlife contacts (n=74) were from Vientiane province. ELISAs detected anti- SARS-CoV-2 Nucleoprotein (N; n=3173 tested) and Spike (S; n=1417 tested) antibodies. Double-positive samples were checked by IgM/IgG rapid tests. Controls were confirmed COVID-19 cases (n=15) and pre-COVID-19 samples (n=265). Seroprevalence for the general community was weighted to account for complex survey sample design, age and sex.

Findings

In pre-COVID-19 samples, 5·

SUBMITTER: Virachith S 

PROVIDER: S-EPMC8277598 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature