Using probabilistic genotypes in linkage analysis of polyploids.

ABSTRACT:

Key message

In polyploids, linkage mapping is carried out using genotyping with discrete dosage scores. Here, we use probabilistic genotypes and we validate it for the construction of polyploid linkage maps. Marker genotypes are generally called as discrete values: homozygous versus heterozygous in the case of diploids, or an integer allele dosage in the case of polyploids. Software for linkage map construction and/or QTL analysis usually relies on such discrete genotypes. However, it may not always be possible, or desirable, to assign definite values to genotype observations in the presence of uncertainty in the genotype calling. Here, we present an approach that uses probabilistic marker dosages for linkage map construction in polyploids. We compare our method to an approach base

SUBMITTER: Liao Y 

PROVIDER: S-EPMC8277618 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature