Asthma Patients Who Stop Asthma Biologics Have a Similar Risk of Asthma Exacerbations as Those Who Continue Asthma Biologics.

ABSTRACT:

Background

There is limited information about outcomes associated with stopping asthma biologics.

Objective

To compare outcomes in people who stopped or continued asthma biologics.

Methods

We identified a cohort of people with asthma who stopped or continued asthma biologics in the Optum Labs Database Warehouse, using a propensity matching method for case and control groups with the variables of age, sex, race, region, insurance, income, specialist access, Charlson comorbidity, specific medical conditions, pre-index exacerbation count, pre-index rescue inhaler pharmacy fills, and pre-index inhaled corticosteroid with or without long-acting β-agonist pharmacy fills. Primary outcome used to assess failure of stopping was an increase of 50% or more in the asthma exacerba

SUBMITTER: Jeffery MM 

PROVIDER: S-EPMC8277704 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature