Infant neurodevelopmental outcomes of prenatal opioid exposure and polysubstance use.

ABSTRACT:

Background

Prenatal opioid exposure has been linked to adverse birth outcomes and delays in infant development. Existing literature is limited by a simple group-differences approach as well as inadequate controls for sociodemographic factors and polysubstance exposure co-occurring with prenatal opioid use.

Method

The current study assessed cumulative opioid exposure (duration of prescribed and illicit opioid use) as a predictor of infant birth outcomes and mother-reported developmental status at three and six months of age, controlling for polysubstance exposure. Participants were predominantly low-income pregnant and peripartum women, oversampled for mothers receiving medication-assisted treatment (MAT) for opioid use disorder. Prenatal opioid and non-opioid substance use w

SUBMITTER: Labella MH 

PROVIDER: S-EPMC8277730 | biostudies-literature | 2021 Jul-Aug

REPOSITORIES: biostudies-literature