Opening the Schrodinger Box: Short- and Long-Range Mammalian Heart Rate Variability.

ABSTRACT:

Background

The interactions between the autonomic nervous system (ANS), intrinsic systems (e.g., endocrine), and internal pacemaker mechanisms govern short (milliseconds-seconds)- and long (seconds-minutes)-range heart rate variability (HRV). However, there is a debate regarding the identity of the mechanism underlying HRV on each time scale. We aim to design a general method that accurately differentiates between the relative contribution of the ANS and pacemaker mechanisms to HRV in various mammals, without the need for drug perturbations or organ isolation. Additionally, we aim to explore the universality of the relative contribution of the ANS and pacemaker system of different mammals.

Methods

This work explored short- and long-range HRVs using published ECG data from do

SUBMITTER: Weiser-Bitoun I 

PROVIDER: S-EPMC8278020 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature