Spatial sensitivity of human circadian response: Melatonin suppression from on-axis and off-axis light exposures.

ABSTRACT: A better understanding of the spatial sensitivity of the human circadian system to photic stimulation can provide practical solutions for optimized circadian light exposures. Two psychophysical experiments, involving 25 adult participants in Experiment 1 (mean age = 34.0 years [SD 15.5]; 13 females) and 15 adult participants in Experiment 2 (mean age = 43.0 years [SD 12.6]; 12 females), were designed to investigate whether varying only the spatial distribution of luminous stimuli in the environment while maintaining a constant spectrally weighted irradiance at the eye could influence nocturnal melatonin suppression. Two spatial distributions were employed, one where the luminous stimulus was presented On-axis (along the line of sight) and one where two luminous stimuli were both presented

SUBMITTER: Nagare R 

PROVIDER: S-EPMC8278206 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature