Renal function outcomes and kidney biopsy features of living kidney donors with hypertension.

ABSTRACT:

Background

The medium- to long-term outcomes of living kidney donors with hypertension compared to normotensive donors are not well understood, especially with the recent changes in hypertension guidelines.

Methods

We studied a cohort of 950 living kidney donors using different definitions of hypertension based on either ≥140/90 or ≥130/80 mmHg thresholds and based on either office or ambulatory blood pressure readings. Microstructural features on kidney biopsy at the time of donation were compared using different definitions of hypertension.

Results

After adjusting for years of follow-up, age, sex, and baseline eGFR, hypertension (by any definition) did not significantly predict an eGFR < 45 ml/min/1.73 m² at a median follow-up of 10 years postdonation, th

SUBMITTER: Merzkani MA 

PROVIDER: S-EPMC8279018 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature