Modelling the relationship between continuously measured glucose and electrocardiographic data in adults with type 1 diabetes mellitus.

ABSTRACT:

Introduction

Type 1 diabetes mellitus (T1DM) is associated with earlier onset of cardiovascular disease. Recent evidence has found hyperglycaemia appears to play a greater role in this association among T1DM compared to T2DM. This study investigates the relationship between glucose and QTc (a key cardiovascular measure) using data from continuous electrocardiogram (ECG) and glucose monitors.

Methods

Seventeen adults with T1DM were recruited at a clinical facility in Ireland. A continuous glucose monitoring system was fitted to each participant that measured glucose every 5 min for 7 days. The participants simultaneously wore a vest with sensors to measure 12-lead ECG data every 10 min for 7 days. Area under the glucose curve (AUC), proportion of time spent in hypoglycaemia a

SUBMITTER: Charamba B 

PROVIDER: S-EPMC8279601 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature