The association between glycaemic control during hospitalization and risk of adverse events: A retrospective cohort study.

ABSTRACT:

Introduction

Hyperglycaemia is common during hospitalization; glycaemic targets in non-critical care settings have not been well studied. We assessed associations between inpatient glycaemic control and adverse events.

Methods

We conducted a retrospective cohort study on non-critically ill medical patients hospitalized in a tertiary care hospital between 2015 and 2018. Mean glycaemia during the first four days of hospitalization was categorized as 4.0-7.0 mmol/L, 7.1-10.0 mmol/L and >10.0 mmol/L. The primary outcome was a composite of adverse events including mortality, infections, acute kidney injury, thromboembolic and cardiovascular events. The secondary outcome was hypoglycaemia, defined as any glycaemia <4.0 mmol/L. Logistic regression was used to assess adverse events,

SUBMITTER: Deng L 

PROVIDER: S-EPMC8279636 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature