Citicoline and Vitamin B₁₂ Eye Drops in Type 1 Diabetes: Results of a 36-Month Pilot Study Evaluating Macular Electrophysiological Changes.

ABSTRACT:

Introduction

Our aim was to evaluate the effects of 36 months of treatment with citicoline and vitamin B₁₂ eye drops on macular function in patients with type 1 diabetes (DM1) with mild signs of non-proliferative diabetic retinopathy (NPDR).

Methods

A prospective, randomized, interventional, monocentric, double-masked study was conducted. Twenty patients with DM1 were enrolled and randomly divided into two groups: the DC group (10 patients; mean age ± standard deviation 46.86 ± 8.78 years) in which one eye of each patient was treated with citicoline and vitamin B₁₂ eye drops (OMK2^®, Omikron Italia srl, Italy, one drop thrice daily) for a period of 36 months; the DP group (10 patients; mean age ± standard deviation 47.89 ± 7.74 years) in which

SUBMITTER: Parisi V 

PROVIDER: S-EPMC8279994 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature