Diffusion tractography for awake craniotomy: accuracy and factors affecting specificity.

ABSTRACT:

Introduction

Despite evidence of correspondence with intraoperative stimulation, there remains limited data on MRI diffusion tractography (DT)'s sensitivity to predict morbidity after neurosurgical oncology treatment. Our aims were: (1) evaluate DT against subcortical stimulation mapping and performance changes during and after awake neurosurgery; (2) evaluate utility of early post-operative DT to predict recovery from post-surgical deficits.

Methods

We retrospectively reviewed our first 100 awake neurosurgery procedures using DT- neuronavigation. Intra-operative stimulation and performance outcomes were assessed to classify DT predictions for sensitivity and specificity calculations. Post-operative DT data, available in 51 patients, were inspected for tract damage.

Resul

SUBMITTER: Voets NL 

PROVIDER: S-EPMC8280000 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature