A global systematic review and meta-analysis on laparoscopic vs open right hemicolectomy with complete mesocolic excision.

ABSTRACT:

Purpose

The aim of this study was to compare the outcomes of right hemicolectomy with CME performed with laparoscopic and open surgery.

Methods

PubMed, Scopus, Web of Science, China National Knowledge Infrastructure, Wanfang Data, Google Scholar and the ClinicalTrials.gov register were searched. Primary outcome was the overall number of harvested lymph nodes. Secondary outcomes were short and long-term course variables. A meta-analysis was performed to calculate risk ratios.

Results

Twenty-one studies were identified with 5038 patients enrolled. The difference in number of harvested lymph nodes was not statistically significant (MD 0.68, - 0.41-1.76, P = 0.22). The only RCT shows a significant advantage in favour of laparoscopy (MD 3.30, 95% CI - 0.20-6.40, P = 0.04).

SUBMITTER: Anania G 

PROVIDER: S-EPMC8280018 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature