Performance Analysis of the National Early Warning Score and Modified Early Warning Score in the Adaptive COVID-19 Treatment Trial Cohort.

ABSTRACT: We sought to validate prognostic scores in coronavirus disease 2019 including National Early Warning Score, Modified Early Warning Score, and age-based modifications, and define their performance characteristics.

Design

We analyzed prospectively collected data from the Adaptive COVID-19 Treatment Trial. National Early Warning Score was collected daily during the trial, Modified Early Warning Score was calculated, and age applied to both scores. We assessed prognostic value for the end points of recovery, mechanical ventilation, and death for score at enrollment, average, and slope of score over the first 48 hours.

Setting

A multisite international inpatient trial.

Patients

A total of 1,062 adult nonpregnant inpatients with severe coronavirus disease 2019 pneumonia.

SUBMITTER: Colombo CJ 

PROVIDER: S-EPMC8280088 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature