Dynamics of amygdala connectivity in bipolar disorders: a longitudinal study across mood states.

ABSTRACT: Alterations in activity and connectivity of brain circuits implicated in emotion processing and emotion regulation have been observed during resting-state for different clinical phases of bipolar disorders (BD), but longitudinal investigations across different mood states in the same patients are still rare. Furthermore, measuring dynamics of functional connectivity patterns offers a powerful method to explore changes in the brain's intrinsic functional organization across mood states. We used a novel co-activation pattern (CAP) analysis to explore the dynamics of amygdala connectivity at rest in a cohort of 20 BD patients prospectively followed-up and scanned across distinct mood states: euthymia (20 patients; 39 sessions), depression (12 patients; 18 sessions), or mania/hypomania (14 pat

SUBMITTER: Rey G 

PROVIDER: S-EPMC8280117 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature