Novel 61-bp Indel of RIN2 Is Associated With Fat and Hatching Weight Traits in Chickens.

ABSTRACT: The Ras and Rab interactor 2 (RIN2) gene, which encodes RAS and Rab interacting protein 2, can interact with GTP-bound Rab5 and participate in early endocytosis. This study found a 61-bp insertion/deletion (indel) in the RIN2 intron region, and 3 genotypes II, ID, and DD were observed. Genotype analysis of mutation sites was performed on 665 individuals from F₂ population and 8 chicken breeds. It was found that the indel existed in each breed and that yellow feathered chickens were mainly of the DD genotype. Correlation analysis of growth and carcass traits in the F₂ population of Xinghua and White Recessive Rock chickens showed that the 61-bp indel was significantly correlated with abdominal fat weight, abdominal fat rate, fa

SUBMITTER: Lin W 

PROVIDER: S-EPMC8280519 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature