Efficacy of phage therapy in pigs: systematic review and meta-analysis.

ABSTRACT: Limits on the use and efficacy of various antibiotics coupled with negative consumer perception of the practice have together spurred substantial research into compounds that could reduce the use antibiotics to control bacterial diseases in pigs. Bacteriophages are often among such potential compounds, and various groups have examined the efficacy of bacteriophages or bacteriophage products in limiting transmission or colonization of targeted bacteria. The study presented here provides a systematic review of such studies followed by a meta-analysis of aggregated data produced by each study. The data set was limited to inputs (n = 19; 576 total observations) from studies where: 1) live pigs were inoculated with a known quantity of challenge bacteria; 2) challenged animals were treated with

SUBMITTER: Desiree K 

PROVIDER: S-EPMC8280926 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature