Identifying Mild Cognitive Impairment in Parkinson's Disease With Electroencephalogram Functional Connectivity.

ABSTRACT:

Objective

Cognitive impairment occurs frequently in Parkinson's disease (PD) and negatively impacts the patient's quality of life. However, its pathophysiological mechanism remains unclear, hindering the development of new therapies. Changes in brain connectivity are related to cognitive impairment in patients with PD, with the dorsolateral prefrontal cortex (DLPFC) being considered the essential region related to PD cognitive impairment. Nevertheless, few studies have focused on the global connectivity responsible for communication with the DLPFC node, the posterior division of the middle frontal gyrus (PMFG) in patients with PD; this was the focus of this study.

Methods

We applied resting-state electroencephalography (EEG) and calculated a reliable functional connectivity

SUBMITTER: Cai M 

PROVIDER: S-EPMC8281812 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature