Mitigating outbreaks in congregate settings by decreasing the size of the susceptible population.

ABSTRACT: While many transmission models have been developed for community spread of respiratory pathogens, less attention has been given to modeling the interdependence of disease introduction and spread seen in congregate settings, such as prisons or nursing homes. As demonstrated by the explosive outbreaks of COVID-19 seen in congregate settings, the need for effective outbreak prevention and mitigation strategies for these settings is critical. Here we consider how interventions that decrease the size of the susceptible populations, such as vaccination or depopulation, impact the expected number of infections due to outbreaks. Introduction of disease into the resident population from the community is modeled as a branching process, while spread between residents is modeled via a compartmental mo

SUBMITTER: Blumberg S 

PROVIDER: S-EPMC8282103 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature