The association between environmental exposures to chlordanes, adiposity and diabetes-related features: a systematic review and meta-analysis.

ABSTRACT: Chlordane compounds (CHLs) are components of technical chlordane listed in the Stockholm convention on persistent organic pollutants identified as endocrine disrupting chemicals (EDCs) and may interfere with hormone biosynthesis, metabolism or action resulting in an unbalanced hormonal function. There is increasing scientific evidence showing EDCs as risk factors in the pathogenesis and development of obesity and obesity-related metabolic syndromes such as type 2 diabetes, but there is no systematized information on the effect of CHLs in humans. Our aim is to identify the epidemiological data on the association between CHLs with adiposity and diabetes using a systematic approach to identify the available data and summarizing the results through meta-analysis. We searched PubMed and Web of

SUBMITTER: Mendes V 

PROVIDER: S-EPMC8282629 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature