The Association Between Plasma Osmolarity and In-hospital Mortality in Cardiac Intensive Care Unit Patients.

ABSTRACT: Objectives: Plasma osmolarity is a common marker used for evaluating the balance of fluid and electrolyte in clinical practice, and it has been proven to be related to prognosis of many diseases. The purpose of this study was to identify the association between plasma osmolarity and in-hospital mortality in cardiac intensive care unit (CICU) patients. Method: All of the patients were divided into seven groups stratified by plasma osmolarity, and the group with 290-300 mmol/L osmolarity was used as a reference group. Primary outcome was in-hospital mortality. The local weighted regression (Lowess) smoothing curve was drawn to determine the "U"-shaped relationship between plasma osmolarity and in-hospital mortality. Binary logistic regression analysis was performed to determine

SUBMITTER: Zhai G 

PROVIDER: S-EPMC8282930 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature