High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder.

ABSTRACT:

Importance

Emergency departments (EDs) sporadically use a high-dose buprenorphine induction strategy for the treatment of opioid use disorder (OUD) in response to the increasing potency of the illicit opioid drug supply and commonly encountered delays in access to follow-up care.

Objective

To examine the safety and tolerability of high-dose (>12 mg) buprenorphine induction for patients with OUD presenting to an ED.

Design, setting, and participants

In this case series of ED encounters, data were manually abstracted from electronic health records for all ED patients with OUD treated with buprenorphine at a single, urban, safety-net hospital in Oakland, California, for the calendar year 2018. Data analysis was performed from April 2020 to March 2021.

Interventions

SUBMITTER: Herring AA 

PROVIDER: S-EPMC8283555 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature