Identification of Risk of Cardiovascular Disease by Automatic Quantification of Coronary Artery Calcifications on Radiotherapy Planning CT Scans in Patients With Breast Cancer.

ABSTRACT:

Importance

Cardiovascular disease (CVD) is common in patients treated for breast cancer, especially in patients treated with systemic treatment and radiotherapy and in those with preexisting CVD risk factors. Coronary artery calcium (CAC), a strong independent CVD risk factor, can be automatically quantified on radiotherapy planning computed tomography (CT) scans and may help identify patients at increased CVD risk.

Objective

To evaluate the association of CAC with CVD and coronary artery disease (CAD) in patients with breast cancer.

Design, setting, and participants

In this multicenter cohort study of 15 915 patients with breast cancer receiving radiotherapy between 2005 and 2016 who were followed until December 31, 2018, age, calendar year, and treatment-adjusted Co

SUBMITTER: Gal R 

PROVIDER: S-EPMC8283560 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature