Effect of Combined Atropine and Patching vs Patching Alone for Treatment of Severe Amblyopia in Children Aged 3 to 12 Years: A Randomized Clinical Trial.

ABSTRACT:

Importance

Patching is often less effective for severe amblyopia because of poor adherence. For the treatment of severe amblyopia, although combined atropine and patching therapy (CAPT) has been found to be efficacious, it is currently unknown whether CAPT is more efficacious than patching alone.

Objective

To compare the efficacy of CAPT vs patching alone in children aged 3 to 12 years with severe amblyopia.

Design, setting, and participants

This single-center randomized clinical trial was conducted from November 2018 to May 2020. The visual acuity (VA) examiner was masked to the treatment groups. The follow-up visits were at 3 months and 6 months. Participants aged 3 to 12 years with severe amblyopia (20/100 to 20/500) resulting from strabismus, anisometropia, or bot

SUBMITTER: Wang S 

PROVIDER: S-EPMC8283662 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature