Ontology highlight
ABSTRACT:
SUBMITTER: Yamamoto T
PROVIDER: S-EPMC8283799 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Yamamoto Tsuyoshi T Caldwell Donald R DR Gandioso Albert A Schnermann Martin J MJ
Photochemistry and photobiology 20190319 4
Uncaging strategies that use near-infrared wavelengths can enable the highly targeted delivery of biomolecules in complex settings. Many methods, including an approach we developed using cyanine photooxidation, are limited to phenol-containing payloads. Given the critical role of amines in diverse biological processes, we sought to use cyanine photooxidation to initiate the release of aryl amines. Heptamethine cyanines substituted with an aryl amine at the C4' position undergo only inefficient r ...[more]