A Single-Step Genome Wide Association Study on Body Size Traits Using Imputation-Based Whole-Genome Sequence Data in Yorkshire Pigs.

ABSTRACT: The body shape of a pig is the most direct production index, which can fully reflect the pig's growth status and is closely related to important economic traits. In this study, a genome-wide association study on seven body size traits, the body length (BL), height (BH), chest circumference (CC), abdominal circumference (AC), cannon bone circumference (CBC), rump width (RW), and chest width (CW), were conducted in Yorkshire pigs. Illumina Porcine 80K SNP chips were used to genotype 589 of 5,572 Yorkshire pigs with body size records, and then the chip data was imputed to sequencing data. After quality control of imputed sequencing data, 784,267 SNPs were obtained, and the averaged linkage disequilibrium (r ²) was 0.191. We used the single-trait model and the two-trait model

SUBMITTER: Liu H 

PROVIDER: S-EPMC8283822 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature