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Efficacy and effectiveness of COVID-19 vaccines against SARS-CoV-2 infection: interim results of a living systematic review, 1 January to 14 May 2021.

ABSTRACT: Evidence on COVID-19 vaccine efficacy/effectiveness (VE) in preventing asymptomatic SARS-CoV-2 infections is needed to guide public health recommendations for vaccinated people. We report interim results of a living systematic review. We identified a total of 30 studies that investigated VE against symptomatic and/or asymptomatic infection. In fully vaccinated individuals, VE against symptomatic and asymptomatic infections was 80-90% in nearly all studies. Fully vaccinated persons are less likely to become infected and contribute to transmission.

SUBMITTER: Harder T

PROVIDER: S-EPMC8284046 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature

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Efficacy and effectiveness of COVID-19 vaccines against SARS-CoV-2 infection: interim results of a living systematic review, 1 January to 14 May 2021.

Harder Thomas T Koch Judith J Vygen-Bonnet Sabine S Külper-Schiek Wiebe W Pilic Antonia A Reda Sarah S Scholz Stefan S Wichmann Ole O

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20210701 28

Evidence on COVID-19 vaccine efficacy/effectiveness (VE) in preventing asymptomatic SARS-CoV-2 infections is needed to guide public health recommendations for vaccinated people. We report interim results of a living systematic review. We identified a total of 30 studies that investigated VE against symptomatic and/or asymptomatic infection. In fully vaccinated individuals, VE against symptomatic and asymptomatic infections was 80-90% in nearly all studies. Fully vaccinated persons are less likel ...[more]

PMID: 34269175

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