Clinical Spectrum, Molecular Characterization, Antifungal Susceptibility Testing of Exophiala spp. From India and Description of a Novel Exophiala Species, E. arunalokei sp. nov.

ABSTRACT:

Introduction

Exophiala spp. are important opportunist pathogens causing subcutaneous or even fatal disseminated infections in otherwise both immunosuppressed and healthy individuals but there are no systematic studies on the isolates of Exophiala species from India.

Methods

Twenty-four isolates of Exophiala species were retrieved from the National Culture Collection of Pathogenic Fungi (NCCPF) and identified phenotypically and by molecular methods (ITS region sequencing) followed by antifungal susceptibility testing (AFST) as per CLSI-M38A3 guidelines. A review of the literature of cases from India was performed up to 1^st January 2021 using the Medline and Cochrane database.

Results

E. dermatitidis (n = 8), E. jeanselmei (

SUBMITTER: Singh S 

PROVIDER: S-EPMC8284318 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature