Cost-effectiveness of point-of-care testing with task-shifting for HIV care in South Africa: a modelling study.

ABSTRACT:

Background

The number of people on antiretroviral therapy (ART) requiring treatment monitoring in low-resource settings is rapidly increasing. Point-of-care (POC) testing for ART monitoring might alleviate burden on centralised laboratories and improve clinical outcomes, but its cost-effectiveness is unknown.

Methods

We used cost and effectiveness data from the STREAM trial in South Africa (February, 2017-October, 2018), which evaluated POC testing for viral load, CD4 count, and creatinine, with task shifting from professional to lower-cadre registered nurses compared with laboratory-based testing without task shifting (standard of care). We parameterised an agent-based network model, EMOD-HIV, to project the impact of implementing this intervention in South Africa over 20 y

SUBMITTER: Sharma M 

PROVIDER: S-EPMC8284441 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature