Ontology highlight
ABSTRACT:
SUBMITTER: Cabrera LE
PROVIDER: S-EPMC8284631 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Cabrera Luz E LE Pekkarinen Pirkka T PT Alander Maria M Nowlan Kirsten H A KHA Nguyen Ngoc Anh NA Jokiranta Suvi S Kuivanen Suvi S Patjas Anu A Mero Sointu S Pakkanen Sari H SH Heinonen Santtu S Kantele Anu A Vapalahti Olli O Kekäläinen Eliisa E Strandin Tomas T
PLoS pathogens 20210706 7
Severe COVID-19 is characterized by extensive pulmonary complications, to which host immune responses are believed to play a role. As the major arm of innate immunity, neutrophils are one of the first cells recruited to the site of infection where their excessive activation can contribute to lung pathology. Low-density granulocytes (LDGs) are circulating neutrophils, whose numbers increase in some autoimmune diseases and cancer, but are poorly characterized in acute viral infections. Using flow ...[more]