Treating chronic diarrhea: A systematic review on Immunoproliferative Small Intestinal Disease (IPSID).

ABSTRACT: Immunoproliferative Small Intestinal Disease (IPSID) is a disease characterized by extra-nodal marginal zone B-cell lymphoma with villous atrophy in the small intestine, causing chronic intermittent non-bloody diarrhea. Although originally associated with the Mediterranean region, this disease is present in many countries worldwide and may have been underreported due to its complicated diagnosis and scarce scientific literature, especially in regards to treatment. This study aims to review IPSID clinical features, therapeutic options, and treatment outcomes to help physicians identify and treat IPSID. Using PRISMA guidelines, a systematic review of articles was conducted on PubMed database with search terms including IPSID, therapy, treatment, and outcomes. Inclusion and exclusion criteria

SUBMITTER: Evangelista-Leite D 

PROVIDER: S-EPMC8284658 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature