Clinical and biochemical signs of polycystic ovary syndrome in young women born preterm.

ABSTRACT:

Objective

It has been suggested that adverse early life exposures increase the risk of developing polycystic ovary syndrome (PCOS) in later life. We hypothesized that women born preterm would have more biochemical and clinical signs of PCOS than women born at term.

Design

The ESTER Preterm Birth Study participants were born in Northern Finland and identified from the Northern Finland Birth Cohort and the Finnish Medical Birth Register. Altogether, 74 women born very or moderately preterm (<34 gestational weeks, VMPT), 127 born late preterm (at 34-36 weeks, LPT), and 184 born full term (≥37 weeks, controls) were included in the analysis (mean age: 23.2 years).

Methods

We measured serum total testosterone and sex hormone-binding globulin (SHBG) and calculated the free a

SUBMITTER: Paalanne M 

PROVIDER: S-EPMC8284903 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature