Applying methods for personalized medicine to the treatment of alcohol use disorder.

ABSTRACT:

Objective

Numerous behavioral treatments for alcohol use disorder (AUD) are effective, but there are substantial individual differences in treatment response. This study examines the potential use of new methods for personalized medicine to test for individual differences in the effects of cognitive behavioral therapy (CBT) versus motivational enhancement therapy (MET) and to provide predictions of which will work best for individuals with AUD. We highlight both the potential contribution and the limitations of these methods.

Method

We performed secondary analyses of abstinence among 1,144 participants with AUD participating in either outpatient or aftercare treatment who were randomized to receive either CBT or MET in Project MATCH. We first obtained predicted individual tr

SUBMITTER: Kuhlemeier A 

PROVIDER: S-EPMC8284918 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature