Population Dynamics of Underdominance Gene Drive Systems in Continuous Space.

ABSTRACT: Underdominance systems can quickly spread through a population, but only when introduced in considerable numbers. This promises a gene drive mechanism that is less invasive than homing drives, potentially enabling new approaches in the fight against vector-borne diseases. If regional confinement can indeed be achieved, the decision-making process for a release would likely be much simpler compared to other, more invasive types of drives. The capacity of underdominance gene drive systems to spread in a target population without invading other populations is typically assessed via network models of panmictic demes linked by migration. However, it remains less clear how such systems would behave in more realistic population models where organisms move over a continuous landscape. Here, we use

SUBMITTER: Champer J 

PROVIDER: S-EPMC8284921 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature