Risks and features of secondary infections in severe and critical ill COVID-19 patients.

ABSTRACT: Objectives Severe or critical COVID-19 is associated with intensive care unit admission, increased secondary infection rate, and would lead to significant worsened prognosis. Risks and characteristics relating to secondary infections in severe COVID-19 have not been described. Methods Severe and critical COVID-19 patients from Shanghai were included. We collected lower respiratory, urine, catheters, and blood samples according to clinical necessity and culture and mNGS were performed. Clinical and laboratory data were archived. Results We found 57.89% (22/38) patients developed secondary infections. The patient receiving invasive mechanical ventilation or in critical state has a higher chance of secondary infections (P<0.0001). The most common infections were re

SUBMITTER: Zhang H 

PROVIDER: S-EPMC8284966 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature