Prenatal paracetamol exposure and neurodevelopmental outcomes in preschool-aged children.

ABSTRACT:

Background

Recent studies have suggested an association between prenatal paracetamol exposure and adverse neurodevelopmental outcomes in children. However, these findings may be confounded by unmeasured factors related to maternal use of paracetamol and child outcomes.

Objective

To examine the association between duration and timing of prenatal paracetamol exposure on parent-reported communication skills, behaviour, and temperament in preschool-aged children, with focus on the role of unmeasured confounding.

Methods

We used data from the Norwegian Mother and Child Cohort Study. Linear and generalised linear models with inverse probability weights and robust standard errors were used to quantify the association between prenatal paracetamol exposure and continuous and c

SUBMITTER: Tronnes JN 

PROVIDER: S-EPMC8285062 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature