Mechanism of Growth Regulation of Yeast Involving Hydrogen Sulfide From S-Propargyl-Cysteine Catalyzed by Cystathionine-γ-Lyase.

ABSTRACT: Pathogenic fungi are recognized as a progressive threat to humans, particularly those with the immunocompromised condition. The growth of fungi is controlled by several factors, one of which is signaling molecules, such as hydrogen sulfide (H₂S), which was traditionally regarded as a toxic gas without physiological function. However, recent studies have revealed that H₂S is produced enzymatically and endogenously in several species, where it serves as a gaseous signaling molecule performing a variety of critical biological functions. However, the influence of this endogenous H₂S on the biological activities occurring within the pathogenic fungi, such as transcriptomic and phenotypic alternations, has not been elucidated so far. Therefore, the present study

SUBMITTER: Gu Z 

PROVIDER: S-EPMC8285084 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature