Effectiveness of a Multicomponent Intervention to Reduce Multidrug-Resistant Organisms in Nursing Homes: A Cluster Randomized Clinical Trial.

ABSTRACT:

Importance

Multidrug-resistant organisms (MDROs) can cause significant morbidity and mortality. Preventing MDROs can reduce the risk of subsequent transmission and infection.

Objective

To determine whether a multicomponent infection prevention intervention can reduce MDRO prevalence in nursing homes (NHs).

Design, setting, and participants

This cluster randomized clinical trial of a multicomponent intervention was conducted in 6 NHs in Michigan from September 2016 to August 2018. Three NHs adopted a multicomponent intervention, while 3 control NHs continued without investigator intervention. Study visits were conducted at baseline; days 7, 14, 21, and 30; and monthly thereafter for up to 6 months or discharge. Visits included clinical data collection and MDRO surveill

SUBMITTER: Mody L 

PROVIDER: S-EPMC8285736 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature