Investigating the Mechanisms of Graded Sensorimotor Precision Training in Adults With Chronic Nonspecific Low Back Pain: Protocol for a Causal Mediation Analysis of the RESOLVE Trial.

ABSTRACT:

Background

Chronic low back pain (CLBP) is a global health problem associated with an increasing burden on individuals, health care systems, and society. Common treatments for people with CLBP produce, on average, small short-term improvements in pain and function compared with minimal care. The RESOLVE trial randomly allocated 276 people with CLBP to a new complex treatment strategy, pain education integrated with graded sensorimotor precision training (RESOLVE), or a sham control. The RESOLVE treatment was developed within a theoretical framework to target possible treatment mechanisms associated with CLBP development and persistence.

Objective

This protocol describes the planned evaluation of these proposed treatment mechanisms. Improved understanding of the mechanisms un

SUBMITTER: Cashin AG 

PROVIDER: S-EPMC8285749 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature