Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence.

ABSTRACT: The transition from childhood to adolescence is marked by pronounced shifts in brain structure and function that coincide with the development of physical, cognitive, and social abilities. Prior work in adult populations has characterized the topographical organization of the cortex, revealing macroscale functional gradients that extend from unimodal (somatosensory/motor and visual) regions through the cortical association areas that underpin complex cognition in humans. However, the presence of these core functional gradients across development as well as their maturational course have yet to be established. Here, leveraging 378 resting-state functional MRI scans from 190 healthy individuals aged 6 to 17 y old, we demonstrate that the transition from childhood to adolescence is reflected

SUBMITTER: Dong HM 

PROVIDER: S-EPMC8285909 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature