Are prescription misuse and illicit drug use etiologically distinct? A genetically-informed analysis of opioids and stimulants.

ABSTRACT:

Background

Drug classes are grouped based on their chemical and pharmacological properties, but prescription and illicit drugs differ in other important ways. Potential differences in genetic and environmental influences on the (mis)use of prescription and illicit drugs that are subsumed under the same class should be examined. Opioid and stimulant classes contain prescription and illicit forms differentially associated with salient risk factors (common route of administration, legality), making them useful comparators for addressing this etiological issue.

Methods

A total of 2410 individual Australian twins [Mage = 31.77 (s.d. = 2.48); 67% women] were interviewed about prescription misuse and illicit use of opioids and stimulants. Univariate and bivariate biometric models p

SUBMITTER: Dash GF 

PROVIDER: S-EPMC8286273 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature