A systematic review and meta-analysis of nab-paclitaxel mono-chemotherapy for metastatic breast cancer.

ABSTRACT:

Background

Although various clinical trials and real-life studies have tried to explore the value of nab-paclitaxel mono-chemotherapy for metastatic breast cancer (MBC), the safety and efficacy of nab-paclitaxel remain unclear which need to be systematically evaluated.

Methods

Electronic searches for prospective clinical trials evaluating nab-paclitaxel monotherapy for MBC were performed. Requisite data were extracted, integrated and analysed from the included studies according to the different study designs using systematic review and meta-analysis. Meta-regression and subgroup analysis were further performed to explore the potential risk factors affecting each individual outcome of interest following nab-paclitaxel monotherapy.

Results

Twenty-two studies with 3287 M

SUBMITTER: Lu H 

PROVIDER: S-EPMC8286600 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature