A Randomized, Controlled, Pilot Study of CPAP for Patients with Chronic Cough and Obstructive Sleep Apnea.

ABSTRACT:

Background

An association between chronic cough and obstructive sleep apnea (OSA) has been reported in prior studies with resolution or improvement in cough after continuous positive airway pressure (CPAP) therapy. Controlled studies of the benefit of CPAP on cough-quality of life measures have not been conducted.

Research question

Does CPAP therapy for OSA improve cough in patients with chronic unexplained cough?

Study design and methods

Patients with unexplained chronic cough (> 2 months duration of cough) and OSA were randomized to receive either CPAP or sham CPAP therapy for 6 weeks. The primary end point was the change in health status assessed with the Leicester Cough Questionnaire (LCQ) in patients treated with CPAP vs. sham CPAP. Secondary end points were chan

SUBMITTER: Sundar KM 

PROVIDER: S-EPMC8286636 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature