Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries.

ABSTRACT: Epidemiological studies mostly focus on single environmental exposures. This study aims to systematically assess associations between a wide range of prenatal and childhood environmental exposures and cognition. The study sample included data of 1298 mother-child pairs, children were 6-11 years-old, from six European birth cohorts. We measured 87 exposures during pregnancy and 122 cross-sectionally during childhood, including air pollution, built environment, meteorology, natural spaces, traffic, noise, chemicals and life styles. The measured cognitive domains were fluid intelligence (Raven's Coloured Progressive Matrices test, CPM), attention (Attention Network Test, ANT) and working memory (N-Back task). We used two statistical approaches to assess associations between exposure and child

SUBMITTER: Julvez J 

PROVIDER: S-EPMC8287594 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature