Risk factors and predictive value of perioperative neurocognitive disorders in elderly patients with gastrointestinal tumors.

ABSTRACT:

Background

This study aims to investigate the risk factors of perioperative neurocognitive disorders (PNDs) mainly including postoperative cognitive dysfunction (POCD) in elderly patients with gastrointestinal tumors, and evaluate its predictive value.

Methods

A total of 222 eligible elderly patients (≥65 years) scheduled for elective gastroenterectomy under general anesthesia were enrolled. The cognitive function assessment was carried out 1 day before surgery and 7 days after surgery. Receiver operating characteristic curve analysis was performed to evaluate the predictive value of risk factors for early POCD. The risk factors for POCD were analyzed using univariate and multivariate logistic regression model.

Results

Of all the 222 enrolled patients, 91 (41.0%) deve

SUBMITTER: Li YL 

PROVIDER: S-EPMC8287702 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature